Skip to Main content Skip to Navigation
Journal articles

Ribosome Biogenesis in Plants: from Functional 45S Ribosomal DNA Organization to Ribosome Assembly Factors

Abstract : The transcription of 18S, 5.8S, and 18S rRNA genes (45S rDNA), cotranscriptional processing of pre-rRNA, and assembly of mature rRNA with ribosomal proteins are the linchpins of ribosome biogenesis. In yeast (Saccharomyces cerevisiae) and animal cells, hundreds of pre-rRNA processing factors have been identified and their involvement in ribosome assembly determined. These studies, together with structural analyses, have yielded comprehensive models of the pre-40S and pre-60S ribosome subunits as well as the largest cotranscriptionally assembled preribosome particle: the 90S/small subunit processome. Here, we present the current knowledge of the functional organization of 45S rDNA, pre-rRNA transcription, rRNA processing activities, and ribosome assembly factors in plants, focusing on data from Arabidopsis (Arabidopsis thaliana). Based on yeast and mammalian cell studies, we describe the ribonucleoprotein complexes and RNA-associated activities and discuss how they might specifically affect the production of 40S and 60S subunits. Finally, we review recent findings concerning pre-rRNA processing pathways and a novel mechanism involved in a ribosome stress response in plants
Document type :
Journal articles
Complete list of metadatas

Cited literature [269 references]  Display  Hide  Download

https://hal-univ-perp.archives-ouvertes.fr/hal-02165772
Contributor : Elisabeth Goetschy <>
Submitted on : Wednesday, January 22, 2020 - 8:35:05 AM
Last modification on : Monday, January 27, 2020 - 9:33:24 AM
Long-term archiving on: : Thursday, April 23, 2020 - 12:50:54 PM

File

1945.full.pdf
Publisher files allowed on an open archive

Identifiers

Collections

Citation

Julio Sáez-Vasquez, Michel Delseny. Ribosome Biogenesis in Plants: from Functional 45S Ribosomal DNA Organization to Ribosome Assembly Factors. The Plant cell, American Society of Plant Biologists (ASPB), 2019, pp.1975-1967. ⟨10.1105/tpc.18.00874⟩. ⟨hal-02165772⟩

Share

Metrics

Record views

137

Files downloads

143