Salen/salan metallic complexes as redox labels for electrochemical aptasensors

Amani Ben Jrad; Hussein Kanso; Delphine Raviglione; Thierry Noguer; Nicolas Inguimbert; Carole Calas-Blanchard

doi:10.1039/c9cc07575e

Journal articles

Salen/salan metallic complexes as redox labels for electrochemical aptasensors

Amani Ben Jrad ^{1, 2, 3} Hussein Kanso ^{4, 1, 2, 5} Delphine Raviglione ³ Thierry Noguer ^{6, 1, 2} Nicolas Inguimbert ^{7, 3} Carole Calas-Blanchard ^{1, 8}

1 BAE - Biocapteurs-Analyses-Environnement

UPVD - Université de Perpignan Via Domitia

2 LBBM - Laboratoire de Biodiversité et Biotechnologies Microbiennes

3 CRIOBE - Centre de recherches insulaires et observatoire de l'environnement

4 LBBM - Laboratoire de Biodiversité et Biotechnologies Microbiennes

5 Faculté de Médecine Dentaire - Univ Libanaise

6 IMAGES - Institut de Modélisation et d'Analyse en Géo-Environnement et Santé

7 Pharmacochimie moléculaire et structurale

8 LBBM - Laboratoire de Biochimie et de Biologie Moléculaire (Université d'Abomey Calavi, Cotonou, Bénin)

Abstract : This work presents the synthesis and characterization of salen/salan metal complexes for their future application as electrochemical labels in affinity sensors. Due to its stability and electrochemical properties, an oxovanadium salan complex was selected and coupled to an estradiol-specific aptamer. The response of the resulting aptasensor was shown to decrease with increasing estradiol concentration.

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Journal articles

Domain :

Chemical Sciences / Organic chemistry

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https://hal-univ-perp.archives-ouvertes.fr/hal-02376397
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Submitted on : Friday, November 22, 2019 - 3:35:30 PM
Last modification on : Wednesday, May 11, 2022 - 12:42:04 PM

Salen/salan metallic complexes as redox labels for electrochemical aptasensors

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Salen/salan metallic complexes as redox labels for electrochemical aptasensors

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